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Las companías fármacas que producen las versiones genéricas, solamente deben comprar una fórmula química y gastar dinero en la producción.
Una droga genérica debe contener los mismos ingredientes activos como la fórmula original.
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He received his medical degree in 1982 and his Ph.

Whilst impressive clinical benefits have been observed for NSCLC with a known driver mutation, acquired resistance is frequently seen and presents us with the next challenge in the goal to deliver unique personalised medicine.

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In patients with resistance to first-generation EGFR TKIs generated by MET amplification, it is unlikely that an irreversible EGFR inhibitor alone would be effective, but the combination of an irreversible EGFR inhibitor and an mTOR inhibitor may be an effective strategy for overcoming resistance ().

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The aim of the present work was to examine the effects of a combined treatment of metformin with gefitinib, a selective EGFR-TKI on NSCLC cell lines.

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The simulation process was conducted in a sequential manner, initially using the PK model to generate the AUC t values for each selected dose regimen, which subsequently defined the PD variables (IC 50 and K tr) via the functional equations (see Supplementary Fig.

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TLG-S criteria are superior to both EORTC and PERCIST for predicting outcomes in patients with metastatic lung adenocarcinoma treated with erlotinib.

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Debido a que este es muy probablemente el resultado de una reducción en el error de estadificación, es decir, una disminución de la probabilidad de pasar por alto los ganglios linfáticos positivos con un número cada vez mayor de muestras de ganglios linfáticos, se indica que una evaluación del estado ganglionar debe incluir entre 11 y 16 ganglios linfáticos.

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